Despite their benefits, chemical sensors face some challenges:

1. Sensor Stability:
   Maintaining long-term accuracy and sensitivity, especially when exposed to sweat, oils, and environmental contaminants.

2. Calibration:
   Sensors often require regular calibration to ensure accurate readings.

3. Skin Compatibility:
   Prolonged skin contact can cause irritation or affect sensor performance.

4. Power Consumption:
   Continuous monitoring can drain wearable device batteries.

5. Data Interpretation:
   Processing chemical data accurately in real-time requires sophisticated algorithms.

6. Cost:
   High-precision chemical sensors can be expensive to produce, increasing device costs.